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| Sl. | Details |
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| 461 | Md. Ohidur Zaman , COVID-19 anxiety and associated factors among university students in Bangladesh Death Studies ,23 Feb 2023 Attachment Read more |
| 462 | Md. Ohidur Zaman , Community resilience to natural disasters: A systemic review of contemporary methods and theories Natural Hazards Research ,1 June 2023 Attachment Read more |
| 463 | Abu Salem , “Islam and Militancy” (Written in Bengali) BINIRMAN (A Regular Publication of Dhaka University Research Society (DURS) ,(December Issue, 2019, University of Dhaka, Bangladesh, pp. 62-65) |
| 464 | Abu Salem , “A Conceptual Framework of Corporate Social Responsibility: A Win-Win Situation” JIBON DARSHON (A Research Journal of Philosophy, published by Department of Philosophy, Jagannath University, Dhaka, Bangladesh) ,(Volume-9, published September 2021, ISSN 2312-7848, PP.287-296) |
| 465 | Abu Salem , “Judging the morality of business practices: moral issues in business focusing on Kant’s categorical imperatives” ANWESAN (A Research Journal of Philosophy, published by Philosophical Association of the Department of Philosophy, University of Rajshahi, Bangladesh). ,(Volume-XIX, December 2020, ISNN 1995-7947, PP.87-96). |
| 466 | Abu Salem , “The Role of Ethics and Morals in Our Daily Life: A Philosophical Insight and Moral Progress” ”. Jagannath University Journal of Arts, Faculty of Arts, ,(Volume 10, No 01, January-June 2020, ISNN: 2519-5816, pp.199-205) |
| 467 | Abu Salem , “Karl Marx’s Revolution and the Consciousness Role of Technology in the Development of Socialism" MANABABIDDA GABESANAPATRA (Double Blind Peer Reviewed Research Journal of Humanities, Published annually by Faculty of Arts, Jatiya Kabi Kazi Nazrul Islam University, Trishal, Mymensingh, Bangladesh) ,(Issue 5, Asharh 1428, July 2021, ISSN 2518-5853, pp. 461-477) |
| 468 | Abu Salem , “Environmental Aesthetics: A Philosophically Informed Understanding of Aesthetic Values and Moral Judgment” ANWESAN (A Research Journal of Philosophy, published by Philosophical Association of the Department of Philosophy, University of Rajshahi, Bangladesh). ,(Volume-XXI, December 2022) |
| 469 |
Cultivating entrepreneurial aspirations: a comprehensive examination of university support, family support, and digital entrepreneurial knowledge on students’ digital entrepreneurial intention, Springer, Tehran University Attachment Read more |
| 470 |
BackgroundThe concurrent Zika Virus (ZIKV) outbreaks in the United States and Northeast Brazil have evoked global surveillance. Zika infection has been correlated with severe clinical symptoms, such as microcephaly, Guillain-Barré syndrome, and other congenital brain abnormalities. Recent data suggest that ZIKV predominantly targets neural progenitor cells leading to neurological impairment. Despite the clinical evidence, detailed experimental mechanism of ZIKV neurotropic pathogenesis has not been fully understood yet. Here we hypothesized that ZIKV produces miRNAs, which target essential host genes involved in various cellular pathways facilitating their survival through immune evasion and progression of disease during brain development. MethodsFrom genome sequence information using several bioinformatic tools, we predicted pri-miRNAs, pre-miRNAs, and finally the mature miRNAs produced by ZIKV. We also identified their target genes and performed functional enrichment analysis to identify the biological processes associated with these genes. Finally, we analyzed a publicly available RNA-seq data set to determine the altered expression level of the targeted genes. ResultsFrom ZIKV genome sequence, we identified and validated 47 putative novel miRNAs. Functional enrichment of the targeted genes demonstrates the involvement of various biological pathways regulating cellular signaling, neurological functions, cancer, and fetal development. The expression analysis of these genes showed that ZIKV-produced miRNAs downregulate the key genes involved in these pathways, which in turn may lead to impaired brain development. ConclusionsOur finding proposes novel ZIKV miRNAs and their targets, which upon experimental validation could help developing new therapeutics to combat ZIKV infection and minimize ZIKV-mediated pathologies. |
